Transplantation of tissue-engineering trachea as alternative to allogenic trachea
نویسندگان
چکیده
منابع مشابه
[Tissue engineering applied to the trachea as a graft].
Tissue engineering offers, through new technologies, an ex vivo generation of organs and functional tissues as grafts for transplants, for the improvement and substitution of biological functions, with an absence of immunological response. The treatment of extended tracheal lesions is a substitution of the affected segment; nevertheless, the allogeneic transplant has failed and the use of synth...
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Tissue-engineering of the trachea is called for based on the clinical consequences of airway pathology. Recent years have witnessed various reports from the tissueengineering field including a few cases of clinical patients receiving an engineered airway. Multiple fields have accelerated in parallel with the concept of tissue decellularization, isolation of stem cells and possible insights in t...
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OBJECTIVES/HYPOTHESIS Scaffold-free cartilage has been used to engineer biocompatible and mechanically stable neotracheas in vivo. The purpose of this animal study was to determine if neotracheal constructs, implanted paratracheally, could successfully be used for segmental tracheal reconstruction. STUDY DESIGN Animal study. METHODS Culture-expanded auricular rabbit chondrocytes were used t...
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Advances in surgical technique and in anaesthesia have made possible a more radical attack on lesions affecting the trachea. Although the number of patients presenting with such a tracheal lesion is small, it is important that they should be treated adequately. Tracheal reconstruction is indicated both for benign and for malignant neoplasms, most of which are found to arise in the lower third. ...
متن کاملSurgery of the Trachea
Surgical procedures on the trachea have only been undertaken within the past 50 years. Knowing the unique blood supply of the trachea and how to reduce tension on any anastomosis are key to a successful outcome. Tracheal conditions requiring surgery usually present with shortness of breath on exertion, and preoperative evaluation involves computed tomography and rigid bronchoscopy. Tracheal res...
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ژورنال
عنوان ژورنال: Grekov's Bulletin of Surgery
سال: 2017
ISSN: 2686-7370,0042-4625
DOI: 10.24884/0042-4625-2017-176-4-110-114